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Thursday, March 29, 2012

WHat what WHAT!!!


What what what

Finally, a scientist at Amgen has come up with something useful in the cancer research sciences.

In cancer science, many "discoveries" don't hold up.  (Reuters) - A former researcher at Amgen Inc has found that many basic studies on cancer -- a high proportion of them from university labs -- are unreliable, with grim consequences for producing new medicines in the future.

So we really ought to look into theories that don't work, and
science that isn't science.
Now that we have published information regarding the things that don't work, we really ought to look into the theories. Retraction Watch get ready! Someone needs to track this guy down. Name names and get an explanation for this:
Part way through his project to reproduce promising studies, Begley met for breakfast at a cancer conference with the lead scientist of one of the problematic studies. 
"We went through the paper line by line, figure by figure," said Begley. "I explained that we re-did their experiment 50 times and never got their result. He said they'd done it six times and got this result once, but put it in the paper because it made the best story. It's very disillusioning." 

It's a Cargo Cult Leader in action. It's rare that we get to see such a species in nature. I would have climbed over the table, strangled him to death, put his head on a plaque and mounted it in my office. 
Ken Kaitlin sums up the world inhabited by the Cargo Cult Leaders.
"If you can write it up and get it published you're not even thinking of reproducibility," said Ken Kaitin, director of the Tufts Center for the Study of Drug Development. "You make an observation and move on. There is no incentive to find out it was wrong."
No incentive? Working in science these days provides no incentive to finding out right from wrong. Hmm.

14 comments:

Anonymous said...

"Working in science these days provides no incentive to finding out right from wrong"

Of course not!

Who cares what you do in science is true or false? This is not important at all. A lot of PIs and golden kids working in their labs have understood that. The ultimate goal in science is to publish at all cost, regardless the way to reach that goal. You become a valuable scientist only if you can accumulate a huge amount of articles in your curriculum vitae even if what you publish is pure bull sh..te

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