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Wednesday, December 21, 2011

The Arrivals

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If you've made up your mind to test a theory, or you want to explain some idea, you should always decide to publish it whichever way it ...

Greatest Loss of 2011

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Daily Hitchens: UK Channel 4 Tribute Imagine an articulate curmudgeon who would dedicate his career to fighting the abuses of scientific aut...
Sunday, December 18, 2011

Most Signficant Fire Burning Out in 2011

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In January of 2010 Alan Sachs of Merck was interviewed about SIRNA, a subsidiary of Merck who specialized in RNA interference. SIRNA was pur...
30 comments:
Tuesday, December 13, 2011

RNAi Strikes Again

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It appears that the only thing RNA interference has accomplished thus far is a whole lot of disappointment. After my first RNAi experiment w...
2 comments:
Friday, December 09, 2011

A Trillion

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One of the interesting 2011 reports on the drug industry came from Burrill and Company. They made the claim that Big Pharma hasn't been ...
Thursday, December 01, 2011

Don Polderman

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One of the things I do from time to time is check the stats on my blog. Most recently I've been getting a lot of hits from people typing...
Wednesday, November 30, 2011

A Tale of Two Janets

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Janet had an important job. Unfortunately, just as she was about to wrap up the show, her boob fell out. The exposure was an embarrassment...
1 comment:
Thursday, November 24, 2011

Geron Research

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What is research ? Wiki says, "Research can be defined as the scientific search for knowledge, or as any systematic investigation, to e...
116 comments:
Sunday, November 20, 2011

Avastin Oh Avastin

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"Sometimes, despite the hopes of investigators, patients, industry and even the FDA itself, the results of rigorous testing can be di...
Friday, November 18, 2011

500 Papers

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Retraction Watch posted the story yesterday of Dr. Don Polderman who was fired from Erasmus University in Rotterdam for scientific misconduc...
Sunday, October 23, 2011

The Art of Journalism

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Bill Moyers recently quoted a mentor of his: "News is what people want to keep hidden; everything else is publicity." Does science...
Wednesday, October 19, 2011

Pharmaplasia and Us

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What ails the pharmaceutical industry? There are many perspectives. The one from the leaders of Seattle is that nothing ails us. We're d...
Monday, October 17, 2011

Why Quit Now?

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I've reached my new location. I'm in a secret hiding place where I have decided to keep taking shots at the Cargo Cults of Science. ...
1 comment:
Wednesday, September 21, 2011

A Cargo Cult Tribesman No More

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After 18 years in Cargo Cult research (how to get the planes to come), I'm calling it quits. The planes never came. As we looked to the ...
3 comments:
Thursday, September 15, 2011

Multiple Intelligence

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Every day in life we experience education. You learn something new every day. There are several concepts here that I think need to be explor...
Wednesday, September 14, 2011

Rice Fields

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Once again Malcolm Gladwell has stopped me dead in my tracks and forced me to rush back to this ridiculous blog. The topic is rice fields. I...
Tuesday, September 13, 2011

They'll Know It When They See It

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Stewart Lyman from Xconomy gives a nice summary of how a drug can act within the body. Drugs can directly stimulate (e.g. morphine) or block...
Sunday, September 11, 2011

Mitigated Speech

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Every case of scientific misconduct involves a powerful scientist and dishonest or disgruntled underlings. In the case of Silvia Bulfone-Pau...
8 comments:
Monday, September 05, 2011

Practical Intelligence and Success

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The biotechnology and pharmaceutical industry continues to try and figure out new ways to encourage innovation. As patents expire and stream...
Monday, August 29, 2011

What To Do With It

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It was not a beautiful paper. Next came the patents. The news that came out today is that the U.S. Patent and Trademark Office (USPTO) h...